<p>The Archean Val-d’Or orogenic gold vein field (Abitibi, Canada) is characterized by quartz-carbonate-tourmaline veins in which at least two temporally distinct Au deposition events are commonly recognized, including Au-Ag-Te-Bi inclusions in pyrite formed during the main quartz mineralizing event, and Au-Te-Bi-Cu-Pb minerals in late quartz ± carbonate brittle veinlets. SEM-CL imaging combined with in situ SIMS oxygen isotope of quartz in four orogenic Au deposits (Beaufor, Lac Herbin, Sigma-2, Triangle) of the Val-d’Or vein field reveal similar quartz vein generations and relative timing. In SEM-CL images, early idiomorphic oscillatory-zoned Qz1 is light grey and formed in vein open space. Qz2, dominant in volume, forms light to medium grey sub-equant grains overprinting Qz1. Later Qz3 forms irregular medium grey bands with sharp or gradual contacts with Qz1 and Qz2, indicating a second recrystallization event. Qz4, minor in volume, forms brittle thin veinlets (&lt; 400&#xa0;μm in width) and stockworks characterized by dark grey luminescence, cutting Qz1, 2 and 3. Qz4 veinlets host Au- Ag-Te-Bi-Cu-Pb minerals. In situ SIMS oxygen isotope analyses of the successive quartz types show a similar, small progressive increase of 𝛅¹⁸O_quartz values, typically by ~ 1‰ between Qz1 and Qz2, and by up to 3.3‰, from Qz1 to the later quartz generations. The 𝛅¹⁸O_quartz values at each deposit follow the 𝛅¹⁸O_quartz regional variation recorded in previous studies, suggesting that later Qz2 and Qz3 are a product of local dissolution and reprecipitation of Qz1. The higher 𝛅¹⁸O_quartz values in Qz2 and Qz3 are interpreted to result from pressure solution/dissolution of Qz1 and reprecipitation either in equilibrium with a fluid with a higher proportion of high 𝛅¹⁸O metamorphic fluids, or from a small amount of cooling. The Qz4 veinlets with Au-Ag-Te-Bi-Cu-Pb minerals result from vein-scale quartz and metal (including gold) dissolution and precipitation into brittle fractures during cooling triggered by a regional thermal event.</p>