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Background <p>With increasing antimicrobial resistance, the attractiveness of antibiotic-sparing approaches in urinary tract infections increases.</p> Objectives <p>Current evidence on alternative treatment options to antibiotics in urinary tract infections.</p> Materials and methods <p>A&#xa0;narrative review of current guidelines and selected literature was performed.</p> Results <p>Rates of symptom relief or symptom resolution are comparable between nonantibiotic and antibiotic therapies. A&#xa0;small risk increase of pyelonephritis remains but does not influence the overall recommendation of an antibiotic-sparing therapy. Outside of the well-defined group of young and healthy women, there is a&#xa0;marked lack of evidence; hence, antibiotics remain standard treatment.</p> Conclusion <p>In nongeriatric healthy women, antibiotic-sparing treatment of urinary tract infections is a&#xa0;viable and increasingly proven alternative. Outside this collective, evidence remains insufficient.</p>

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Unkomplizierter Harnwegsinfekt: Es geht auch ohne Antibiose

  • 期刊论文

  • 发表日期：

    2026年5月4日

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  • Sebastian Graf

摘要

Background

With increasing antimicrobial resistance, the attractiveness of antibiotic-sparing approaches in urinary tract infections increases.

Objectives

Current evidence on alternative treatment options to antibiotics in urinary tract infections.

Materials and methods

A narrative review of current guidelines and selected literature was performed.

Results

Rates of symptom relief or symptom resolution are comparable between nonantibiotic and antibiotic therapies. A small risk increase of pyelonephritis remains but does not influence the overall recommendation of an antibiotic-sparing therapy. Outside of the well-defined group of young and healthy women, there is a marked lack of evidence; hence, antibiotics remain standard treatment.

Conclusion

In nongeriatric healthy women, antibiotic-sparing treatment of urinary tract infections is a viable and increasingly proven alternative. Outside this collective, evidence remains insufficient.