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Background <p>Inflammatory spinal disorders include infectious spondylodiscitis and noninfectious spondyloarthritis. Their clinical differentiation and distinction from degenerative conditions are crucial.</p> Objective <p>This review aims to clearly describe infectious and noninfectious spondylitis, highlighting diagnostic and therapeutic challenges.</p> Materials and methods <p>Analysis of current literature and clinical experience regarding infection pathways, clinical symptoms, and characteristic findings in imaging modalities (magnetic resonance imaging [MRI], computed tomography [CT], X‑ray).</p> Results <p>Infectious spondylodiscitis typically arises through hematogenous or iatrogenic routes, predominantly affecting older patients and presenting specific changes detectable by MRI and CT. Noninfectious spondylarthritis, such as axial spondyloarthritis, typically manifests as enthesitis with characteristic structural lesions. MRI is highly sensitive in identifying active inflammatory lesions, while CT and&#xa0;X-ray are advantageous for visualizing chronic structural changes.</p> Conclusion <p>Diagnosing inflammatory spinal disorders remains challenging and requires a&#xa0;combination of clinical and imaging findings. Unified definitions and standardized diagnostic procedures are essential to minimize incorrect assessment and facilitate targeted therapy.</p>

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Spondylitis und Spondylodiszitis

  • 期刊论文

  • 发表日期：

    2025年6月25日

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  • Torsten Diekhoff,
  • Dominik Deppe

摘要

Background

Inflammatory spinal disorders include infectious spondylodiscitis and noninfectious spondyloarthritis. Their clinical differentiation and distinction from degenerative conditions are crucial.

Objective

This review aims to clearly describe infectious and noninfectious spondylitis, highlighting diagnostic and therapeutic challenges.

Materials and methods

Analysis of current literature and clinical experience regarding infection pathways, clinical symptoms, and characteristic findings in imaging modalities (magnetic resonance imaging [MRI], computed tomography [CT], X‑ray).

Results

Infectious spondylodiscitis typically arises through hematogenous or iatrogenic routes, predominantly affecting older patients and presenting specific changes detectable by MRI and CT. Noninfectious spondylarthritis, such as axial spondyloarthritis, typically manifests as enthesitis with characteristic structural lesions. MRI is highly sensitive in identifying active inflammatory lesions, while CT and X-ray are advantageous for visualizing chronic structural changes.

Conclusion

Diagnosing inflammatory spinal disorders remains challenging and requires a combination of clinical and imaging findings. Unified definitions and standardized diagnostic procedures are essential to minimize incorrect assessment and facilitate targeted therapy.