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Background <p>Long-term survivors of childhood and adolescent cancer face a&#xa0;lifelong increased risk of new diseases as a&#xa0;consequence of the cancer and its treatment. The S2k guidelines “Long-term follow-up care of childhood and adolescent cancer survivors—Avoiding, recognizing and treating late effects” summarizes the existing evidence and forms a&#xa0;basis for risk-adapted screening options.</p> Objective <p>To develop long-term follow-up (LTFU) recommendations for childhood and adolescent cancer survivors.</p> Material and methods <p>The guidelines were developed chapter-wise by experts selected by the guideline committee. The core statements and recommendations for action were discussed and revised in a&#xa0;structured consensus process within the guideline committee. The final guideline text was approved by all members of the guideline committee.</p> Results <p>A&#xa0;total of 90&#xa0;LTFU recommendations for 14&#xa0;organ (systems) were developed in 15&#xa0;expert working groups, approved and summarized in the S2k guidelines.</p> Conclusion <p>Risk-adapted screening facilitates early diagnosis, treatment and in some cases prevention of late effects. This can reduce the increased morbidity and late mortality in long-term childhood cancer survivors and improve their health-related quality of life. Interdisciplinary aftercare teams address the complex needs of this patient group and enable holistic LTFU care, taking both somatic and psychological sequelae into account.</p>

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Langzeitnachsorge nach Krebs im Kindesalter

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月2日

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  • Judith Gebauer,
  • Thorsten Langer

摘要

Background

Long-term survivors of childhood and adolescent cancer face a lifelong increased risk of new diseases as a consequence of the cancer and its treatment. The S2k guidelines “Long-term follow-up care of childhood and adolescent cancer survivors—Avoiding, recognizing and treating late effects” summarizes the existing evidence and forms a basis for risk-adapted screening options.

Objective

To develop long-term follow-up (LTFU) recommendations for childhood and adolescent cancer survivors.

Material and methods

The guidelines were developed chapter-wise by experts selected by the guideline committee. The core statements and recommendations for action were discussed and revised in a structured consensus process within the guideline committee. The final guideline text was approved by all members of the guideline committee.

Results

A total of 90 LTFU recommendations for 14 organ (systems) were developed in 15 expert working groups, approved and summarized in the S2k guidelines.

Conclusion

Risk-adapted screening facilitates early diagnosis, treatment and in some cases prevention of late effects. This can reduce the increased morbidity and late mortality in long-term childhood cancer survivors and improve their health-related quality of life. Interdisciplinary aftercare teams address the complex needs of this patient group and enable holistic LTFU care, taking both somatic and psychological sequelae into account.