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<p>A&#xa0;22-year-old male patient with a&#xa0;clinical picture similar to that of sepsis was diagnosed with macrophage activation syndrome in adult Still’s disease on the basis of clinical and laboratory criteria. The diagnostic work-up included the differentiated clarification of a&#xa0;persistent fever syndrome and the differential diagnosis of hemophagocytic lymphohistiocytosis. Immunosuppressive therapy with dexamethasone, immunoglobulins and anakinra was initiated and a&#xa0;sustained clinical remission was achieved.</p>

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Eine seltene Differenzialdiagnose des „fever of unknown origin“

  • 期刊论文

  • 发表日期：

    2025年3月10日

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  • Sabrina Welland,
  • Linus Risser,
  • René Abu Isneineh

摘要

A 22-year-old male patient with a clinical picture similar to that of sepsis was diagnosed with macrophage activation syndrome in adult Still’s disease on the basis of clinical and laboratory criteria. The diagnostic work-up included the differentiated clarification of a persistent fever syndrome and the differential diagnosis of hemophagocytic lymphohistiocytosis. Immunosuppressive therapy with dexamethasone, immunoglobulins and anakinra was initiated and a sustained clinical remission was achieved.