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Hepatotoxizität durch Albendazol: sichere Alternativen bei Echinokokkosetherapie

  • Laura Muana Wilhelm,
  • Joschka Bachmann,
  • Markus Cornberg,
  • Heiner Wedemeyer,
  • Bernd Heinrich

摘要

Infection with Echinococcus multilocularis leads to the clinical manifestation of alveolar echinococcosis. This is characterized by the formation of alveolar liver tumours, which usually disintegrate necrotically in the course of the disease. Pseudocysts are formed. Especially in the early stages, curative resection followed by long-term treatment with albendazole is recommended. However, the majority of patients are not amenable to curative surgery. In these cases, albendazole therapy is the first-choice treatment. We present a rare case of albendazole-associated hepatitis in a patient with inoperable Echinococcus multilocularis infection, with a favourable outcome following a change in treatment to mebendazole.