<p>Digitalization opens up a&#xa0;wide range of didactic and organizational possibilities for examinations in medical curricula. This article provides a&#xa0;systematic overview of the potential, challenges, and current implementation scenarios of digital examinations—from computer-based exams and video-based formats to virtual reality applications. The focus lies on both the didactic opportunities for assessing medical competencies and on the new challenges related to organization, technology, and legal certainty. The article also highlights the dynamic role of artificial intelligence. Its integration creates new possibilities for formative and competence-oriented assessment but also raises questions regarding equal opportunities, fraud prevention, and ethical considerations. The successful implementation of digital examinations requires a&#xa0;clear orientation towards didactic goals, close cooperation among various university stakeholders, and continuous professional development. Overall, it is evident that digital examinations contribute to increased efficiency and improved examination quality, while also requiring ongoing evaluation and continuous improvement.</p>