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<p>This case report describes a&#xa0;patient with localized laryngeal immunoglobulin light chain (AL) amyloidosis. The larynx is one of the most common sites of manifestation of localized amyloidosis. Amyloidosis leads to benign, tumor-like lesions caused by the deposition of insoluble protein aggregates, so-called fibrils. The current patient presented with the main symptom of hoarseness. Amyloidosis is most commonly treated by surgical resection of the mass. However, depending on the extent and course of disease, other therapeutic approaches are also feasible, which are discussed in this review.</p>

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Seltene Ursache der Heiserkeit – Falldarstellung und Kurzübersicht zur laryngealen Amyloidose

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月17日

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  • Hannah Schützenmeister,
  • Rahel Schwotzer,
  • Jakob Becker,
  • Nathalie Nierobisch,
  • Daniel Runggaldier,
  • Jörg E. Bohlender

摘要

This case report describes a patient with localized laryngeal immunoglobulin light chain (AL) amyloidosis. The larynx is one of the most common sites of manifestation of localized amyloidosis. Amyloidosis leads to benign, tumor-like lesions caused by the deposition of insoluble protein aggregates, so-called fibrils. The current patient presented with the main symptom of hoarseness. Amyloidosis is most commonly treated by surgical resection of the mass. However, depending on the extent and course of disease, other therapeutic approaches are also feasible, which are discussed in this review.