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<p>Wells syndrome is a&#xa0;rare eosinophilic dermatosis that is commonly treated with systemic corticosteroids. We report the successful use of the anti-interleukin‑5 antibody mepolizumab in a&#xa0;76-year-old woman with Wells syndrome. This case demonstrates that mepolizumab may represent an effective treatment option after failure of standard therapies. Its use should also be considered in the absence of peripheral blood eosinophilia or other eosinophilic disorders.</p>

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Rasches Ansprechen eines Wells-Syndroms ohne Bluteosinophilie oder weitere eosinophile Erkrankungen auf Mepolizumab

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月27日

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  • Finn Abeck,
  • I. Hansen-Abeck,
  • F. Ohm,
  • U. Siemann-Harms,
  • N. Booken,
  • S. W. Schneider

摘要

Wells syndrome is a rare eosinophilic dermatosis that is commonly treated with systemic corticosteroids. We report the successful use of the anti-interleukin‑5 antibody mepolizumab in a 76-year-old woman with Wells syndrome. This case demonstrates that mepolizumab may represent an effective treatment option after failure of standard therapies. Its use should also be considered in the absence of peripheral blood eosinophilia or other eosinophilic disorders.