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<p>A&#xa0;63-year-old man with cutaneous melanoma metastases showed a&#xa0;strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a&#xa0;significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment’s response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.</p>

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Nichtinvasive Bildgebung kutaner Melanommetastasen

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月29日

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  • Oliver Mayer,
  • Rebecca Schönherr,
  • Julia Welzel,
  • Sandra Schuh

摘要

A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment’s response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.