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Background <p>Occasionally, tinea is a&#xa0;differential diagnostic option in lesions of nummular atopic eczema. Mycological diagnostics can yield quite unexpected results.</p> Objectives <p>Evaluation of the detection of rare geophilic dermatophytes on atopic eczema, using mycological data and its clinical interpretation.</p> Methods <p>Detailed conventional and genetic mycological work-up of scales collected from atopic eczema; correlation of the findings with the clinical context and the pertinent literature.</p> Results <p>On a&#xa0;lesion of nummular atopic dermatitis two rare geophilic dermatophytes were detected synchronously: <i>Arthroderma&#xa0;(A.) onychocola </i>and <i>A.&#xa0;quadrifidum</i>. This was only the third isolation of <i>A.&#xa0;onychocola</i> ever and the first one on glabrous skin and in Germany. The strain grew on human stratum corneum and perforated hair. <i>A.&#xa0;quadrifidum</i> did not show unusual features. No pathogenetic relevance of this twofold colonization was noted regarding the atopic eczema.</p> Conclusion <p>Obviously, <i>A.&#xa0;onychocola</i> is more prevalent than has been assumed up to now. Geophilic dermatophytes detected on atopic dermatitis are not necessarily pathogenetically relevant for eczema—such a&#xa0;colonization needs to be critically interpreted in relation to its clinical context. The determinants that allow geophilic dermatophytes to persist on human skin are still not understood.</p>

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Arthroderma onychocola plus Arthroderma quadrifidum auf atopischem Ekzem

  • 期刊论文

  • 发表日期：

    2025年6月24日

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  • J. Brasch,
  • K. Voss,
  • K. A. Langen,
  • S. Weidinger

摘要

Background

Occasionally, tinea is a differential diagnostic option in lesions of nummular atopic eczema. Mycological diagnostics can yield quite unexpected results.

Objectives

Evaluation of the detection of rare geophilic dermatophytes on atopic eczema, using mycological data and its clinical interpretation.

Methods

Detailed conventional and genetic mycological work-up of scales collected from atopic eczema; correlation of the findings with the clinical context and the pertinent literature.

Results

On a lesion of nummular atopic dermatitis two rare geophilic dermatophytes were detected synchronously: Arthroderma (A.) onychocola and A. quadrifidum. This was only the third isolation of A. onychocola ever and the first one on glabrous skin and in Germany. The strain grew on human stratum corneum and perforated hair. A. quadrifidum did not show unusual features. No pathogenetic relevance of this twofold colonization was noted regarding the atopic eczema.

Conclusion

Obviously, A. onychocola is more prevalent than has been assumed up to now. Geophilic dermatophytes detected on atopic dermatitis are not necessarily pathogenetically relevant for eczema—such a colonization needs to be critically interpreted in relation to its clinical context. The determinants that allow geophilic dermatophytes to persist on human skin are still not understood.