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<p>Pigment disorders are commonly observed in patients with systemic sclerosis. They can occur in up to 50% of those affected and include both hypo- and diffuse hyperpigmentation. The latter can be an indicator of vascular involvement and suggest a&#xa0;severe course of the disease. We report on the case of a&#xa0;patient with diffuse cutaneous systemic sclerosis who, in addition to severe vascular complications including digital ulcerations, necrosis, and autoamputations, developed diffuse hyperpigmentation.</p>

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Diffuse Hyperpigmentierung bei systemischer Sklerose

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年3月26日

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  • Sven-Niklas Burmann,
  • Johanna Matull,
  • Frank Oellig,
  • Jörg H. W. Distler,
  • Alexander Kreuter,
  • Andrea-Hermina Györfi

摘要

Pigment disorders are commonly observed in patients with systemic sclerosis. They can occur in up to 50% of those affected and include both hypo- and diffuse hyperpigmentation. The latter can be an indicator of vascular involvement and suggest a severe course of the disease. We report on the case of a patient with diffuse cutaneous systemic sclerosis who, in addition to severe vascular complications including digital ulcerations, necrosis, and autoamputations, developed diffuse hyperpigmentation.