Scholarlink

Purpose <p>There is no clear consensus on whether peritoneal lavage should be used in complicated appendicitis, nor which solution is ideal. This study evaluated the outcomes of two different intraperitoneal lavage solutions in adult patients with complicated appendicitis. </p> Methods <p>We conducted a prospective analytical comparative study including adult patients with complicated appendicitis treated by open appendectomy between January 2023 and July 2024. Patients were allocated according to intraoperative availability of lavage solution to either saline solution (SS) lavage or stabilized isotonic sodium hypochlorite solution (SISHS) lavage. Primary outcomes were length of hospital stay, postoperative complications within 30 days, and total direct treatment costs. </p> Results <p> A total of 120 patients were included (60 per group). Baseline demographic and clinical characteristics were comparable. Mean hospital stay was significantly shorter in the SISHS group compared with the SS group (1.86 ± 0.60 vs 6.15 ± 5.59 days; p = 0.004). Postoperative complications, including wound infection, seroma, abdominal wall abscess, intra-abdominal abscess, postoperative ileus, pain, and abdominal distension, were less frequent in the SISHS group (all p &lt; 0.05). Reoperations were required in 21 patients in the SS group and in none of the SISHS group. Total direct treatment costs were 42.8% lower in the SISHS group. </p> Conclusion <p>These findings suggest that SISHS lavage may offer favorable postoperative outcomes, including shorter hospital stays, lower complication rates, and reduced direct treatment costs in adult patients undergoing open appendectomy for complicated appendicitis. Further controlled studies are needed to confirm these findings.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Saline solution vs. stabilized isotonic sodium hypochlorite lavage in complicated appendicitis: a comparative study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月16日

查看全文
  • Milton Alberto Muñoz-Leija,
  • Marion Carolina Alemán-Jiménez,
  • Ramón González-Lemus,
  • Raúl Dario Martínez-Carvajal,
  • Saúl Tóvar-López,
  • Alejandro Quiroga-Garza,
  • Armando Magdaleno Joya-Munguía,
  • Heliodoro Plata-Álvarez

摘要

Purpose

There is no clear consensus on whether peritoneal lavage should be used in complicated appendicitis, nor which solution is ideal. This study evaluated the outcomes of two different intraperitoneal lavage solutions in adult patients with complicated appendicitis.

Methods

We conducted a prospective analytical comparative study including adult patients with complicated appendicitis treated by open appendectomy between January 2023 and July 2024. Patients were allocated according to intraoperative availability of lavage solution to either saline solution (SS) lavage or stabilized isotonic sodium hypochlorite solution (SISHS) lavage. Primary outcomes were length of hospital stay, postoperative complications within 30 days, and total direct treatment costs.

Results

A total of 120 patients were included (60 per group). Baseline demographic and clinical characteristics were comparable. Mean hospital stay was significantly shorter in the SISHS group compared with the SS group (1.86 ± 0.60 vs 6.15 ± 5.59 days; p = 0.004). Postoperative complications, including wound infection, seroma, abdominal wall abscess, intra-abdominal abscess, postoperative ileus, pain, and abdominal distension, were less frequent in the SISHS group (all p < 0.05). Reoperations were required in 21 patients in the SS group and in none of the SISHS group. Total direct treatment costs were 42.8% lower in the SISHS group.

Conclusion

These findings suggest that SISHS lavage may offer favorable postoperative outcomes, including shorter hospital stays, lower complication rates, and reduced direct treatment costs in adult patients undergoing open appendectomy for complicated appendicitis. Further controlled studies are needed to confirm these findings.