Early vs. late surgery in thoracic spine fractures: impact on clinical outcomes in polytrauma patients
摘要
Thoracic spine fractures are common in polytrauma patients and are frequently associated with high-energy trauma and severe systemic injury. Although early surgical stabilization may improve clinical outcomes by reducing complications and hospital stay, the optimal timing for intervention remains controversial. Evidence is limited regarding the impact of surgical timing in patients with varying injury severity scores.
PurposeTo investigate, in a cohort study, the relationship between surgical timing and clinical outcomes in polytrauma patients with thoracic spine fractures.
Study desing/settingThis was a retrospective cohort study performed at a Level 1 trauma center, involving consecutive patients with thoracic spine fractures who underwent surgical treatment between 2009 and 2015. All procedures were conducted by an experienced spine surgery team using standardized operative and perioperative protocols.
Patient sampleThe study included 57 polytrauma patients with thoracic spine fractures who underwent surgical stabilization between 2009 and 2015. Patients were divided into four groups according to Injury Severity Score (≥ 25 vs. < 25) and timing of surgery (< 8 h vs. > 8 h).
Outcomes measuresThe primary outcome was hospital length of stay, used as a surrogate for clinical recovery. Secondary outcomes included ICU length of stay, volume of blood transfused, number of vertebral segments stabilized, postoperative complications, and in-hospital mortality. These measures were selected to assess the impact of surgical timing on short-term clinical outcomes.
MethodsA total of 57 polytrauma patients who underwent surgical treatment for thoracic spine fractures were included in the study. Patients were categorized based on two variables: time to surgery (early: <8 h vs. late: >8 h) and Injury Severity Score (ISS) upon admission (high: ≥25 vs. low: <25), resulting in four distinct groups. Key variables analyzed included blood transfusions, number of fixation segments, surgery-related complications, and length of hospital and Intensive Care Unit (ICU) stays.
ResultsComparison of groups with similar ISS revealed that patients in the early surgery groups experienced significantly reduced hospitalization duration. Furthermore, statistical analysis indicated a significant positive correlation between hospitalization length and both the volume of blood transfused and the number of vertebral segments stabilized.
ConclusionThis study adds valuable insight into optimal management strategies for thoracic spine fractures in polytrauma patients. Our findings suggest that early surgical intervention is associated with improved clinical outcomes, highlighting the importance of timely treatment in enhancing patient recovery.