<p>Despite major advances, morbidity and mortality after cardiac arrest remain high. Postresuscitation care requires a&#xa0;multimodal, time-coordinated approach. The International Liaison Committee on Resuscitation (ILCOR) model describes four phases of brain injury, explaining the failure of single-target therapies. Cardiac arrest centers consolidate expertise and improve survival and neurological outcomes in observational studies, although randomized trials remain inconclusive. Hypoxia must be avoided, while hyperoxia should not be pursued; a&#xa0;MAP of 60–65 mm Hg is adequate. Immediate PCI is mandatory in STEMI but not without ST-elevation. ECPR may benefit selected patients if implemented early. Temperature management now focuses on fever prevention. Prognostication must be multimodal and appropriately timed to avoid premature withdrawal of life-sustaining therapy.</p>

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Postreanimationstherapie auf der Intensivstation

  • Sebastian Wolfrum,
  • Tobias Wengenmayer

摘要

Despite major advances, morbidity and mortality after cardiac arrest remain high. Postresuscitation care requires a multimodal, time-coordinated approach. The International Liaison Committee on Resuscitation (ILCOR) model describes four phases of brain injury, explaining the failure of single-target therapies. Cardiac arrest centers consolidate expertise and improve survival and neurological outcomes in observational studies, although randomized trials remain inconclusive. Hypoxia must be avoided, while hyperoxia should not be pursued; a MAP of 60–65 mm Hg is adequate. Immediate PCI is mandatory in STEMI but not without ST-elevation. ECPR may benefit selected patients if implemented early. Temperature management now focuses on fever prevention. Prognostication must be multimodal and appropriately timed to avoid premature withdrawal of life-sustaining therapy.