Purpose <p>This study aimed to assess the endothelialization of drug-eluting stents (DES) 3&#xa0;months after implantation for the treatment of symptomatic vertebral artery stenosis using endovascular optical coherence tomography (OCT).</p> Methods <p>Between March and May 2024, OCT was performed on patients 3&#xa0;months (90 ± 7&#xa0;days) after undergoing surgery for stent implantation at the vertebral artery ostium in our center.</p> Results <p>Nine DES were implanted in nine patients. The mean follow-up period was 95.6 ± 12.6 days. OCT findings showed the vertebral artery lumen with fully endothelialized stent struts covered by neointima in all nine patients 3&#xa0;months after implantation, indicating complete endothelialization.</p> Conclusions <p>Complete endothelialization of vertebral artery DES occurred 3&#xa0;months after implantation, providing a&#xa0;theoretical basis for potentially reducing the duration of DAPT 3&#xa0;months. Further clinical studies are essential to validate these findings.</p>

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Follow-up Optical Coherence Tomography Evaluation of Endothelialization in Drug-eluting Stents for Symptomatic Vertebral Artery Stenosis: a Report of Nine Cases

  • Bo Lei,
  • Li Chen,
  • Wenzhang Luo,
  • Ying Chen,
  • Honggang Wu,
  • Jiachuan Wu,
  • Shu Chen,
  • Niandong Zheng,
  • Daobao Zhang

摘要

Purpose

This study aimed to assess the endothelialization of drug-eluting stents (DES) 3 months after implantation for the treatment of symptomatic vertebral artery stenosis using endovascular optical coherence tomography (OCT).

Methods

Between March and May 2024, OCT was performed on patients 3 months (90 ± 7 days) after undergoing surgery for stent implantation at the vertebral artery ostium in our center.

Results

Nine DES were implanted in nine patients. The mean follow-up period was 95.6 ± 12.6 days. OCT findings showed the vertebral artery lumen with fully endothelialized stent struts covered by neointima in all nine patients 3 months after implantation, indicating complete endothelialization.

Conclusions

Complete endothelialization of vertebral artery DES occurred 3 months after implantation, providing a theoretical basis for potentially reducing the duration of DAPT 3 months. Further clinical studies are essential to validate these findings.