Scholarlink

<p>The estrogen sulfotransferase (EST), also called sulfotransferase 1E1 (SULT1E1), plays an important role in estrogen homeostasis by sulfonating and deactivating estrogens. The identification and characterization of EST inhibitors has been an active field of research. The EST inhibitors can not only be used as tool compounds to characterize the biochemical and pathophysiological functions of EST, but also have therapeutic potential due to the implications of EST and its regulation in hormone-dependent and independent pathological conditions. This review article is intended to provide a historical perspective and summary of the recent progress in the development and characterization of EST inhibitors.</p><p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Estrogen sulfotransferase inhibitors, triclosan and beyond

  • 期刊论文

  • 发表日期：

    2025年10月4日

查看全文
  • NP Syamprasad,
  • Kevin Ren,
  • Wen Xie

摘要

The estrogen sulfotransferase (EST), also called sulfotransferase 1E1 (SULT1E1), plays an important role in estrogen homeostasis by sulfonating and deactivating estrogens. The identification and characterization of EST inhibitors has been an active field of research. The EST inhibitors can not only be used as tool compounds to characterize the biochemical and pathophysiological functions of EST, but also have therapeutic potential due to the implications of EST and its regulation in hormone-dependent and independent pathological conditions. This review article is intended to provide a historical perspective and summary of the recent progress in the development and characterization of EST inhibitors.