<p>In the perturbative treatment of interacting quantum field theories, if the interaction Lagrangian changes adiabatically in a finite interval of time, secular growths may appear in the truncated perturbative series also when the interaction Lagrangian density is returned to be constant. If this happens, the perturbative approach does not furnish reliable results in the evaluation of scattering amplitudes or expectation values. In this paper we show that these effects can be avoided for adiabatically switched-on interactions, if the spatial support of the interaction is compact and if the background state is suitably chosen. We start considering equilibrium background states and show that, when thermalisation occurs (interaction Lagrangian of spatial compact support), secular effects are avoided. Furthermore, no secular effects pop up if the limit where the Lagrangian is supported everywhere in space is taken after thermalisation (large time limit), in contrast to the reversed order. This result is generalized showing that if the interaction Lagrangian is spatially compact, secular growths are avoided for generic background states which are only invariant under time translation and to states whose explicit dependence of time is not too strong. Finally, as an application, the presented theorems are used to study a complex scalar and a Dirac field, on a background KMS state, in a classical external electromagnetic potential and the contribution to the two point-function given by a generic loop diagram arising from a second order perturbative expansion.</p>