<p>We address the question of whether holographic entropy inequalities obeyed in static states (by the RT formula) are always obeyed in time-dependent states (by the HRT formula), focusing on the case where the bulk spacetime is 2 + 1 dimensional. An affirmative answer to this question was previously claimed by Czech-Dong. We point out an error in their proof when the bulk is multiply connected. We nonetheless find strong support, of two kinds, for an affirmative answer in that case. We extend the Czech-Dong proof for simply-connected spacetimes to spacetimes with <i>π</i>₁ = <i>ℤ</i> (i.e. 2-boundary, genus-0 wormholes). Specializing to vacuum solutions, we also numerically test thousands of distinct inequalities (including all known RT inequalities for up to 6 regions) on millions of randomly chosen configurations of regions and bulk spacetimes, including three different multiply-connected topologies; we find no counterexamples. In an appendix, we prove some (dimension-independent) facts about degenerate HRT surfaces and symmetry breaking.</p><p>A video abstract is available at https://www.youtube.com/watch?v=ols92YU8rus.</p>